The risk of venous thromboembolism associated with the use of tranexamic acid and other drugs used to treat menorrhagia: a case-control study using the General Practice Research Database. Winkler UH. The effect of tranexamic acid on the quality of life of women with heavy menstrual bleeding. Bonnar J, Sheppard BL. Treatment of menorrhagia during menstruation: randomised controlled trial of ethamsylate, mefenamic acid, and tranexamic acid.
Treatment of menorrhagia with tranexamic acid. A double-blind trial. Br Med J. Comparative study of tranexamic acid and norethisterone in the treatment of ovulatory menorrhagia. Br J Obstet Gynaecol. A comparison of flurbiprofen, tranexamic acid, and a levo-norgestrel-releasing intrauterine contraceptive device in the treatment of idiopathic menorrhagia.
Am J Obstet Gynecol. Ylikorkala O, Viinikka L. Comparison between anti-fibrinolytic and antiprostaglandin treatment in the reduction of increased menstrual blood loss in women with intrauterine contraceptive devices. Role of tranexamic acid in management of dysfunctional uterine bleeding in comparison with medroxyprogesterone acetate. J Obstet Gynaecol. Accessed August 30, Each independent review is provided by authors who have no financial association with the drug manufacturer.
This content is owned by the AAFP. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. Contact afpserv aafp. Want to use this article elsewhere? Get Permissions. Read the Issue. You should not use this medication if you are allergic to tranexamic acid, if you have problems with the blood vessels in your eyes, or if you have ever had a stroke, blood clot, or bleeding in your brain.
Before using this medicine, tell your doctor if you have kidney disease, leukemia, a history of endometriosis, or if your menstrual cycles are less than 21 days apart or longer than 35 days apart. Do not start taking Lysteda until your period has started. Do not take it for longer than 5 days in a row. Talk with your doctor if your symptoms do not improve after 2 cycles of treatment. Use a barrier form of birth control such as a condom or diaphragm with spermicide.
Hormonal contraception such as birth control pills, injections, implants, skin patches, and vaginal rings may increase your risk of stroke, blood clot, or heart attack if they are used at the same time as Lysteda. Tranexamic acid is a man-made form of an amino acid protein called lysine. Tranexamic acid prevents enzymes in the body from breaking down blood clots.
Lysteda is used to treat heavy menstrual bleeding. This medication will not treat premenstrual syndrome PMS. To make sure you can safely take Lysteda, tell your doctor if you have any of these other conditions:. It is not known whether tranexamic acid will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
Tranexamic acid can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended.
Follow the directions on your prescription label. Lysteda is usually taken three times per day for up to 5 days during your menstrual period.
Do not take more than 6 tablets in one hour period. Take the missed dose as soon as you remember. Then take your next dose at least 6 hours later. Do not take extra medicine to make up the missed dose. Overdose symptoms may include severe forms of some of the side effects listed in this medication guide. Avoid using a hormonal form of birth control such as birth control pills, injections, implants, skin patches, and vaginal rings. Do not take this medicine when you do not have your period. You should wait until your monthly period has started before taking this medicine.
This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions. The dose of this medicine will be different for different patients.
Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. It is very important that your doctor check your progress while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Tell your doctor if you are using birth control pills or other types of birth control eg, patch, vaginal ring, or intrauterine device.
You should not use this medication if you are also using combination hormonal contraception because it may increase your chance of having a blood clot, heart attack, or stroke. Your risk is even higher if you are overweight, if you smoke cigarettes, or if you are over 35 years of age.
This medicine may cause serious allergic reactions including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have shortness of breath, trouble breathing, chest tightness, flushing of the face, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine. Call your doctor right away if you have any eye problems, such as a change in your vision.
Your doctor will want you to have your eyes checked by an ophthalmologist eye doctor. If this medicine does not reduce your bleeding after two menstrual cycles or if it seems to stop working, check with your doctor.
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